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March 3, 2013 Interviews, Medications, Phosphate Binders No comments

The Dose-Relativity of Sevelamer to Lanthanum under Real-World Conditions: Implications for Patient Management

Hemodialysis.com Author Interview: J Brian Copley, MD FASN FACP

Hemodialysis.com: What are the main findings of the study?

Dr. Copley: Dose relativity, with respect to the various phosphate binders, refers to the comparative dosage of phosphate binder required to achieve similar levels of phosphorus control.

This is a post hoc analysis of a post marketing, phase IV study of patients with ESRD and hyperphosphatemia in a real-world clinical practice setting in the US.

Marie Benz, MD on Google+

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- Impaired Kidney Function at Hospital Discharge and Long-Term Renal and Overall Survival in Patients Who Received CRRT
  
  Hemodialysis.com eInterview with Dr. Susanne Stads
  Department of Intensive Care
  Erasmus Medical Center, H-626
  PO Box 2040, 3000 CA Rotterdam, the Netherlands.
  
  Hemodialysis.com: What are the main findings of the study?
  
  Dr. Stads: Acute Kidney Injury requiring renal replacement therapy is associated with high in-hospital mortality. Little is known about renal recovery in surviving patients and the impact of impaired kidney function on long-term renal and overall survival.
  
  In a retrospective cohort study, we evaluated the association between impaired kidney function at hospital discharge with long-term renal and overall survival. The median follow up in our cohort was 8.5 years (range 1-17 years). Only 35% (n=170) of patients in our cohort were discharged with an estimated GFR > 60 ml/min per 1.73m². An estimated GFR < 30 ml/min per 1.73m² was a strong and independent predictor for decreased long-term survival and poor renal survival.
  
  Marie Benz, MD on Google+
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